ACHAPTER I
BACKGROUND
Do you know “Lupus” Indonesian adolescent that mischievous, cute and friendly. He have sister and his sister name is Lulu and often call he “front wave” because his from wave and bubble gum become his characteristic. But this Lupus no Lupus from wave lupus is autoimmune disease.
¯ There are several the explanation ventured for the term lupus erythematosus.
§ In various account, some doctor though the rash resembled the pattern of furon a wolf face common explanation for the term is
§ In other accounts, doctor though that the rash, which was often more severe in earlier centuries, created lesion that resembled wolf bites or scratches
§ Another account claims that the term “Lupus” did no come from latin at all, but from the term for a French style of mask that women, reportedly, wore to conceal the rash of their face. That mask is called “loup” French for “wolf”
§ Another common explanation for the term is that the disease course involves repeated attacks like those of voracious predator, leaving behind the red bloches.
Lupus disease come true be familiar since last era. The first people guess that lupus cause is wolf bite that is red spots on around noise and chick. That notion giving occasion this disease later be said to be Lupus. Lupus in Latin word that mean is wolf scientific name of Lupus is Systemic Lupus Erythematosus. Diseases emerged cause reaction effect more immune system. This disease have fast spread ability attack productive women average adult period, until now lupus victim the domination of women.
Lupus disease have the unique name, but do not cheated with the unique name if hear Lupus, the name have impression funny. But who supposition this disease is dangerous disease that difficult detection. This disease cause until now not clear but be after opinion about this disease however no definite. This disease have fast spread ability attack productive women average adult period, until now lupus victim the domination of women.
Systemic lupus Erythematosus is a chronic autoimmune disease than can be fatal though with recent medical advances, fatalities are becoming increasing rare. As with other autoimmune disease the immune system attack the body cell and tissue, resulting inflammation and tissue damaged. Systemic lupus Erythematosus can effect any part of the body, but most often harms the heart, joints, skin, lungs, blood vessels, liver, kidneys, and nervous system. The course of the disease is unpredictable, with periods of illness alternating with remission. Lupus can occur at any age, and is most common in women, particularly of non European descent. Lupus treatable symptomatically, mainly with corticosteroid and immunosuppressant, though there is currently no cure. Survival in patient with Systemic lupus Erythematosus in the united state, Canada, and Europe is approximately 95% at 5 years, 90% at 10 years, and 75% at 20 years.
Lupus is disease that involves the immune system and affects about 1, 5 million Americans nearly 90% of those diagnosed with the disease are female. Normally, a person immune system works by producing immunity cells and antibodies, special substances that fight germs and infection.
Victim of lupus disease called Odapus. To Odapus skin rash emerged red spots on the skin but no contagious, for diagnose this disease needed blood or skin biopsy. Both of them for immune control when the Lupus active.
When the person has Lupus, the immune system goes into overdrive and can’t tell difference between some of body normal, healthy cells and germs that can cause infection. So the immune system responds by making autoantibody that attack the body normal cells.
Body has invulnerability for attacked the disease and keep still healthy. Although what happen if invulnerability exactly attacked body organ that healthy so that lupus disease guess have relation with immunology system that more. This disease included mysterious because the doctor sometime dizzy for diagnose this disease. This disease make lupus victim loss of beautiful skin, beautiful face and age. People can infection this disease will feel tired for long time, sick on the body muscle, fever and hair fall. If have two of lupus symptom the people must check up to specialist doctor. Because this disease has many symptom, so women that attacked two or more symptom must the suspicious infection of lupus. For the total recover from this disease, like the difficult, because doctor more focus of medical treatment that have the quality while. More focus for restrain spread this disease and not attacked body organ vital.
In addition to taking medicine, a big part of treating lupus may involve lifestyle changes. For a lot people with lupus, paying close attention to certain health habits can help prevents their symptoms from flaring up. Getting enough rest and avoiding becoming too busy or overly stressed are helpful. Eating well and exercising regularly can also help a person avoid a flare.
People with lupus can learn to manage the disease to minimize its impact on their lives. Some teens work with a health care team, getting help from a rheumatologist, a nephrologist (a doctor who specializes in kidney problems), a nurse practitioner, and a social worker. Because lupus can differ from one person to another, the team will create a special treatment plan based on the person individual needs.
Parts of managing lupus is controlling the symptoms and preventing flares. A flares is period of time when the disease get worse. During a flare, a person feels much more tired, sick, feverish, and achy then usual and it can also harm important body organs.
When it comes to staying healthy, sometimes the things a person with lupus doesn’t do can be just as important as those they do. Rheumatologist recommend that people with lupus don’t spend time in the sun unless they wear lost of sunscreen and protective clothing because ultraviolet rays can bring on a flare.
Smoking, drinking, and drugs are also a bad idea for teens with lupus. Alcohol can throw off the balance of certain medications, a dangerous situation for someone with lupus. Tattooing and body piercing are also off limits because of an increased risk of infection. Infection can be a risk because some of the medications doctors prescribe for lupus suppress the immune system and don’t allow the body to fight infection as it usually would.
Doctor also advises that teen girls with lupus stay away from birth control pills containing the hormone estrogen; researchers believe that the extra estrogen in the pills can make symptom worse. Doctor suggest that teens who are sexually active use other types of contraception instead.
With the right medicines and paying attention to their health habits, most teens with lupus can go to school, enjoy many activities, play sport, and hangout with their friend. If you have a friend or classmate who has lupus, ask how you can help and over your support. For example, if your friend is sick, keeping him or her up to date on what’s going on in school by bringing notes and homework home is always a big help.
This disease science medical called Systemic Lupus Erythematosus is when the attacked body entire or internal system of human. In the immunology science those disease is inverse of cancer or HIV/AIDS. At the lupus, become overacting body about stimulation from the something strange and make too many antibodies or like the protein that infect for fighting body network.
Like the contest in the small book “care of lupus” lupus is the other term lupus erythematosus. Physic change that very clear is at the skin. Like that visible at the lupus victim is sandbar skin and slick like balloon. In technical term someone can be said suffer lupus disease when the bodies become allergy to self.
The total victim of lupus until now just a little. According of American documents found of 14,6 until 50,8. In Indonesia can found around 50000 has victim. Whereas in Ciptomangukusumo hospital Jakarta from 71 case that the deal begin since 1991 until end 1996, 1 from 23 victims is men. Nowadays many people don’t know lupus disease because lupus disease is common thing in environment.
Notable Patients
Ø Stephanie Smits ; artist who died of Systemic Lupus Erythematosus complication in 1969 at the age of 22. The anti-smith antigen was discovered in her and is the basis of a Systemic Lupus Erythematosus diagnostic test.
Ø Caroline Dorough-Cochran, sister of Howie D of the backstreet boys, who founded the Dorough Lupus foundation in her memory.
Ø Louisa May Alcott American author
Ø Donald byrne Chess player who died from complication of lupus in 1976
Ø Inday Ba, a Swedish born actress who died from complication of lupus at age 32
Ø J Dilla, a hip-hop producer and beatmaker wh died of the disease in 2006
Ø Hugh Gaitskell, British Politican
Ø Michael Jackson, pop superstar diagnosed with the disease in the 1984
Ø Charles Kuralt, Former Anchor Of CBS , died of the disease in 1997
Ø Ferdinand Marcos Former philippine president, who died from complication of lupus in 1989
Ø Marry Elizabeth McDonough, American Actrees
Ø Flannery O’connor, merican fiction writer who died of the disease in 1964
Ø Elaine Paige, British actress and singer
Ø Tim Raines, former major league baseball player, primarily with the montreal expos and Chicago white sox
Ø Seal, singer
Ø Mercedes scelba-shorte, American next top model season two runner up and model
Ø Ray Waltson, Character Actor
History of Lupus
Medical historian have theorized that people with porphyria generated folklore stories of vampire and werewolves, due to photosensitivity, scarring, hair growth, and porphyrin brownish red stained teeth in severe recessive forms of porphyria.
The history of lupus erythematosus can be divided into three periods: classical, neoclassical, and modern. The classical period began when the disease was first recognized in the Middle Ages and saw the description of the dermatological manifestation of othe disorder. The term lupus is attributed to 12th century physician rogerius. One manifestation of lupus is abnormalities in apoptosis, a type of programmed cell death in which aging or damaged cells are neatly disposed of as part of normal growth or functioning.
Problem Formulating
Ø What is the meaning of systemic lupus Erythematosus ?
Ø What is the effect of systemic Lupus Erythematosus?
Effect for Body?
Effect for Environment?
Ø What is the cause of Systemic Lupus Erythematosus ?
Ø What is the complication of systemic lupus Erythematosus ?
Ø Why lupus diseases dominate attacked women?
Ø What is determent of this disease?
Ø What is the manner for decrease this disease spread?
Ø What is the medical treatment for patient of lupus?
Purpose
Ø Description is the meaning of systemic Lupus Erythematosus
Ø Description is the effect of Systemic Lupus Erythematosus
Body?
Environment?
Ø Description is the complication of Systemic Lupus Erythematosus
Ø Description is the cause of Systemic Lupus Erythematosus
Ø Tell about medical treatment for patient of lupus
Ø Description why lupus diseases dominate attacked women
Ø Tell about the manner for decrease this disease spread
Ø Give the determent of this disease.
Benefit
The benefit of these working paper is giving as more knowledge about Systemic Lupus Erithematosus and make people understand about this disease dangerous specially are women. This disease attack the productive women so I hope this paper can help every women for care to her body health, because this disease effect is very dangerous and can make Odapus death. Systemic Lupus Erithematosus also can make miscarriage and difficult for pregnant because this disease generally attack the women. Until now many people do know about this disease, Lupus is common disease. In this paper I can description about lupus disease specially Systemic Lupus Erithematosus this is one of type lupus disease.
Problem identification
The three types of Lupus are:
Systemic Lupus Erythematosus
All called Systemic Lupus Erythematosus , this the type of lupus that most people mean when they talk about the disease. Give it is name by 19th Century French Doctor who tthought that the facial rash of some people with lupus look like the bite or scratch of a wolf (Lupus is latin word is Wolf and Erythematosus is latin word is for red).
Systemic Lupus Erythematosus is the most serious form of Lupus. 15% of the people who have Systemic Lupus Erythematosus first start to feel sick when they are. Systemic lupus Erythematosus first start to feel sick when they are teens. Systemic lupus Erythematosus can affect the skin, joints, and tendons. It may also affect organs like the brains, heart, lungs, and kidneys.
Discoid Lupus
This type of Lupus is a skin disease that causes a rash on the face, neck, scalp, and ears. It is a much more rare form lupus than Systemic lupus Erythematosus, although about 10% of people of discoid lupus will develop a mild form of Systemic lupus Erythematosus. It doesn’t affect other body organs the way that systemic lupus erythematosus can. The rash of discoid lupus can cause scaring though.
Drug induced Lupus
This type of lupus is caused by a reaction to certain kinds of medicines. For example, some types of antiseizure medicines and acne medicines can cause this kind of lupus in teens. Drug induced is similar to Systemic lupus Erythematosus in the ways it affects the body, but once a person stop taking the medicine, the symptoms usually go away.
Between three type of lupus that very dangerous is Systemic Lupus Erythematosus because this have complication in body organs. Systemic lupus Erythematosus give the impact is death, and miscarriage the specially for female. So that with this paper i can description about one of the type lupus disease is Systemic Lupus Erythematosus because that i give delimitation of problem is Systemic lupus Erythematosus type. In this paper I just tell about Systemic lupus Erythematosus type because I think the type is very dangerous an interesting. I can tell detail about lupus disease but I just description about what is the mean of lupus? What cause is lupus? What is the effect? What is the symptom? Etc.
The symptom of lupus sometime not aware because however like minor important symptom, so that things make people specially women consider this disease is usual.
Sometimes many doctor difficult for diagnosed this disease because this disease like allergy disease so many doctor sometimes dizzy for diagnosed. For know lupus symptom must do Ribose Antinuclear Antibody Test (ANA) and Deoxyribose Nucleic Acid Double-Stranded (DNA DS) in the chapter II I write detail about Ribose Antinuclear Antibody Test (ANA) and Deoxyribose Nucleic Acid Double-Stranded (DNA DS).
Lupus is not understood well enough to be prevented, but when the disease develops, quality of life can be improved through flare prevention. The warning signs of an bite impeding flare include increased fatigued, pain, rash, fever, abdominal discomfort, headache and dizziness. Early recognition of warning signs and good communication with a doctor can help individuals with lupus remain active, experience less pain, and results medical visit.
Systemic lupus Erythematosus is one of several disease known as “the great imitators” because is symptoms vary so widely it often mimic or is mistaken for other illness and because the symptom come and go unpredictably. Diagnose can be elusive with patient sometimes suffering unexplained symptom and untreated Systemic lupus Erythematosus for years. Common initial and chronic complaint are fever, malaise, joint pains, myalgias, fatigued, and temporary loss of cognitive abilities. Because they are so often seen with other disease, these signs and symptom are not part of the diagnostic criteria for Systemic lupus Erythematosus. When occurring in conjunction with other signs and symptom, however, they are considered suggestive.
Systemic lupus Erythematosus have complication in odapus body, however that complication happen to patient of Systemic lupus Erythematosus type, because the type is the dangerous Lupus. The complication is that serious condition because this disease already spread to body organ, generally this type cause is death.
Identification problem for this lupus is problem of lupus, cause is lupus, diagnosed the disease, complication of lupus, medical treatment for patient of lupus, determent the disease, and lupus effect for body and environment.
